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Dogs and Cats. DES is used primarily to treat urinary incontinence in spayed females. Estrogens increase urethral tone and help to prevent leaking or dribbling of urine. DES usually is effective。

Diethylstilbestrol is generally well tolerated in female dogs. A mild side effect of diethylstilbestrol may include some blood spotting from the vagina in unspayed female dogs. Serious side effects are generally associated with。

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